The 12th stage is likely to be prey for the sprinters. The first 100 kilometres of the stage are slightly undulating through the Emilia-Romagna countryside. After the village of Quattro Castella, the terrain becomes completely flat. The last 70 kilometres to the finish are completely flat and lead along wide, mostly straight roads. As is usual with city crossings, the riders have to reckon with the typical obstacles in urban areas. The riders cross the finish line once before tackling a 27-kilometre circuit. The last three kilometres have only one bend about 500 metres before the finish. The roads are wide, tarmac and in good condition. The finishing straight is 450 metres long and runs along an eight-metre-wide road.
After the strenuous previous day, this predominantly flat stage offers the sprinters in the peloton an excellent opportunity to play to their strengths. The profile of the stage is perfect for a bunch sprint at the finish in Viadana. The slightly undulating first 100 kilometres should not be a major obstacle for the sprinters' teams. On the last 70 kilometres, which are completely flat, they will be able to position themselves and get their sprinters into position. The decisive factor will be how well the teams can guide their captains through the streets of the finish town and launch them onto the 450 metre long finishing straight. The favourites for the day's victory are likely to be the classic sprinters in the peloton. Breakaway attempts by individual riders or smaller groups are to be expected, but have little chance of success due to the route profile. The overall classification riders will probably try to get through the day without losing any time and without crashing in order to save energy for the difficult stages ahead.